Project title: Role of scleraxis as a master regulator of cardiac fibroblast fate.
The position is for a doctoral student in the Department of Physiology and Pathophysiology. The project focuses on using single cell RNA sequencing and spatial transcriptomics approaches to define and understand cardiac fibroblast populations in the healthy and failing heart in order to reveal novel mechanisms driving cardiac fibrosis - a common yet currently untreated condition that contributes to heart failure and death. The broader goal is to identify new approaches for the development of anti-fibrotic treatments.
Candidates are expected to have an MSc or equivalent degree in a field relevant to the project, such as cardiovascular physiology, biochemistry, or bioinformatics. Ideally, candidates will have published peer-reviewed papers in their field. A stipend commensurate with Tri-Council recommendations will be provided.
